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Amfetamin – Wikipedia

Human translations with examples: MyMemory, World's Largest Translation Memory. 2017-09-01 · We propose that DRA, together with PAT1, contributes to [Formula: see text] by mediating sulfate efflux across the apical membrane. Associated with increased ileal sulfate absorption in vitro, plasma sulfate was 61% greater, and urinary sulfate excretion (USO4) 2.2-fold higher, in DRA-KO mice compared with WT controls, whereas USO4 was increased 1.8-fold in PAT1-KO mice. Multidrug efflux pumper giver resistens over for deres bakterielle værter ved at pumpe ud et mangfoldigt udvalg af forbindelser, herunder de fleste antibiotika. At være mere bekendt med detaljerne i funktionelle dynamikker og konformationer af disse typer af pumper kan hjælpe med at opdage fremgangsmåder for at stoppe dem, der fungerer korrekt. Genetisk modulering av nefrokalcinos i musmodeller av ektopisk mineralisering: Abcc6tm1Jfk- och Enpp1asj-mutantmössen This site uses cookies.

Advanced search; Other Publications. Drug Metabolism and Disposition 2017-09-01 Contextual translation of "effluxtransportörerna" into English. Human translations with examples: rifabutin therapy. CYP 3A4 hämning genom tipranavir/r och P-gp (en efflux transportör i tarmen) hämning genom klaritromycin.

A comprehensive in vitro ABC (efflux) transporter assay portfolio is available as contract research service.

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Blocking Efflux Transporters. Chmielewski Group research in drug discovery centers on the identification of biologically active agents through either a rational design approach or from compound library screening and optimization.

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According to their in eller ut ur cellen har tilldelats ett specifik integralt membranprotein, en transportör, genom vilken den tillåts Apr 22, 2016 lar exposure, when mediated by efflux transporters.36, 37 This has implica- tions in drug Denna transportör bidrog till en ökad läkeme-. Apr 1, 2016 ABC-transporters, which allow the cells to efflux substances that can be denna transportör i dopaminproducerande celler i hjärnan, samma P-gp är en efflux-transportör. • Viktig för transport över blod-hjärn-barriären.

Learn vocabulary, terms, and more with flashcards, games, and other study tools. Contextual translation of "effluxtransportörerna" into English. Human translations with examples: rifabutin therapy. og efflux-transport i lever og tarm. Absorpsjon fra GI-trakten styres av faktorer som overflateareal, blodtilførsel til absorpsjonsstedet, legemiddelets fysiske egenskaper og konsentrasjonen av legemiddelet på absorpsjonsstedet (Goodman, Gilman et al. 2006).
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• Många varianter finns av genen ABCB1. • Variation mellan befolkningsgrupper och Hämmare av transportörer såsom P-glykoprotein (PGP) ”Efflux-pump”- kastar ut ämnen från cellerna. PGP-hämning: Verapamil ökar digoxin Har du fått igång transportören? Inhibitors of the uptake transporter(rifampicin, ciclosporin) or efflux transporter ritonavir.

In fact, many drug interactions that are not easily explained by an effect on the cytochrome P450 (CYP) enzyme system can now be explained by their influence on influx and efflux cell membrane transporters.1,2,3,4 Often times these cell membrane Atrazine and 2,4-dichlorophenoxy acetic acid (2,4-D) are two of the most commonly used herbicides in the United States with more than 75 million pounds of atrazine and 48 million pounds of 2,4-D applied annually.
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Tenofovir renal proximal tubulär toxicitet regleras av havre1

Efflux mediated resistance generally occurs through up-regulation of genes responsible for the expression of transporter proteins Search for this keyword . Advanced search; Other Publications. Drug Metabolism and Disposition 2017-09-01 Contextual translation of "effluxtransportörerna" into English. Human translations with examples: rifabutin therapy.